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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL3
All Species:
11.82
Human Site:
S496
Identified Species:
21.67
UniProt:
Q8IZE3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZE3
NP_065156.5
742
82857
S496
L
Q
T
G
D
P
F
S
Q
P
I
K
F
P
I
Chimpanzee
Pan troglodytes
XP_513987
742
82925
S496
L
Q
T
G
D
P
F
S
Q
P
I
K
F
P
I
Rhesus Macaque
Macaca mulatta
XP_001096051
736
82375
S496
L
Q
T
G
D
P
F
S
Q
P
I
K
F
P
I
Dog
Lupus familis
XP_537198
743
82483
Q496
Q
T
G
D
K
F
P
Q
P
I
K
F
P
M
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBQ7
735
81315
H496
Q
T
G
D
Q
F
S
H
T
I
K
F
P
M
N
Rat
Rattus norvegicus
Q5M9F8
807
89107
I530
R
D
Q
A
F
K
T
I
R
S
F
L
S
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514536
1518
163635
S1121
A
P
A
P
F
S
R
S
A
G
L
H
L
W
F
Chicken
Gallus gallus
NP_001012613
698
77220
E476
P
D
W
S
E
P
E
E
T
E
N
E
K
T
V
Frog
Xenopus laevis
Q561M0
827
91284
A587
T
G
G
G
A
Q
D
A
S
P
S
E
G
A
P
Zebra Danio
Brachydanio rerio
NP_955951
768
85305
S497
I
S
E
R
T
V
F
S
S
E
M
S
F
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610175
683
77833
G463
V
E
D
F
M
V
S
G
S
P
L
P
Q
E
S
Honey Bee
Apis mellifera
XP_001123124
613
70111
D394
V
G
I
K
D
T
N
D
H
L
V
S
A
T
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177952
810
89574
D508
T
G
V
A
V
G
E
D
A
M
V
S
A
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
85.5
N.A.
80.7
21.9
N.A.
31.8
61.9
21.8
51.9
N.A.
25.7
28.4
N.A.
33.5
Protein Similarity:
100
99.1
96.7
90.3
N.A.
87.7
38.5
N.A.
37.4
71.5
39
67.5
N.A.
45.9
49.7
N.A.
50.7
P-Site Identity:
100
100
100
0
N.A.
0
0
N.A.
6.6
6.6
13.3
26.6
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
100
0
N.A.
0
13.3
N.A.
13.3
26.6
26.6
46.6
N.A.
26.6
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
16
8
0
0
8
16
0
0
0
16
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
8
16
31
0
8
16
0
0
0
0
0
0
0
% D
% Glu:
0
8
8
0
8
0
16
8
0
16
0
16
0
8
0
% E
% Phe:
0
0
0
8
16
16
31
0
0
0
8
16
31
0
8
% F
% Gly:
0
24
24
31
0
8
0
8
0
8
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
8
0
0
8
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
8
0
16
24
0
0
0
24
% I
% Lys:
0
0
0
8
8
8
0
0
0
0
16
24
8
8
0
% K
% Leu:
24
0
0
0
0
0
0
0
0
8
16
8
8
0
24
% L
% Met:
0
0
0
0
8
0
0
0
0
8
8
0
0
16
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
16
% N
% Pro:
8
8
0
8
0
31
8
0
8
39
0
8
16
31
8
% P
% Gln:
16
24
8
0
8
8
0
8
24
0
0
0
8
0
0
% Q
% Arg:
8
0
0
8
0
0
8
0
8
0
0
0
0
0
8
% R
% Ser:
0
8
0
8
0
8
16
39
24
8
8
24
8
8
8
% S
% Thr:
16
16
24
0
8
8
8
0
16
0
0
0
0
16
0
% T
% Val:
16
0
8
0
8
16
0
0
0
0
16
0
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _